La maladie de Parkinson au Canada (serveur d'exploration)

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Clozapine in the treatment of parkinsonian patients with dopaminomimetic psychosis

Identifieur interne : 004A04 ( Main/Exploration ); précédent : 004A03; suivant : 004A05

Clozapine in the treatment of parkinsonian patients with dopaminomimetic psychosis

Auteurs : E. C. Wolters ; T. A. Hurwitz ; E. Mak ; P. Teal ; F. R. Peppard ; R. Remick ; S. Calne ; D. B. Calne

Source :

RBID : Pascal:91-0384576

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English descriptors

Abstract

In a double-blind placebo-controlled study, we evaluated the effects of clozapine (75 to 250 mg/day, mean 170.8) on dopaminomimetic psychosis and parkinsonian disability. Clozapine prevented deterioration of psychosis during the increase of dopaminomimetics in the 3 patients who completed the study. Worsening of parkinsonism occurred in 3 of 6 patients


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Le document en format XML

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<term>Degenerative disease</term>
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<term>Sleep (drug effects)</term>
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<term>Psychose toxique</term>
<term>Stimulant dopaminergique</term>
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<div type="abstract" xml:lang="en">In a double-blind placebo-controlled study, we evaluated the effects of clozapine (75 to 250 mg/day, mean 170.8) on dopaminomimetic psychosis and parkinsonian disability. Clozapine prevented deterioration of psychosis during the increase of dopaminomimetics in the 3 patients who completed the study. Worsening of parkinsonism occurred in 3 of 6 patients</div>
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<name sortKey="Mak, E" sort="Mak, E" uniqKey="Mak E" first="E." last="Mak">E. Mak</name>
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{{Explor lien
   |wiki=    Wicri/Canada
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   |flux=    Main
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   |clé=     Pascal:91-0384576
   |texte=   Clozapine in the treatment of parkinsonian patients with dopaminomimetic psychosis
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